Cytopathic and Non-cytopathic Biotypes of Border Disease Virus Induce Polypeptides of Different Molecular Weight with Common Antigenic Determinants

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Characterization of the immune response of cattle against non-cytopathic and cytopathic biotypes of bovine viral diarrhoea virus.

Cross-infection studies of normal calves infected with homologous pairs of non-cytopathic and cytopathic bovine viral diarrhoea virus (BVDV) showed significant differences in both humoral and cell-mediated immune responses against either biotype over a period of 5 months. Serological assays after primary intranasal inoculation showed striking significant (P < 0.05) differences between biotypes....

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Lysosomal Enzymes in Cells Infected with Cytopathic and Non-cytopathic Viruses

In chick embryo cells infected with fowl plague virus, an avian strain of influenza A which produces cytopathic effects, lysosomal enzymes were released from the particulate to the supernatant fraction of homogenates within 6 hours of infection. This change occurred in the presence of high concentrations of parafluorophenylalanine, suggesting that the changes were due to redistribution of prefo...

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Cytopathic effect of PPR vaccine virus

The present study describes the cytopathic effect of two different Peste des petits ruminants (PPR) vaccine virus strains presently being used in the country, in vero cells. The cytopathic effect (CPE) was visible from 4 day post infection in Sungri vaccine virus strain where as Arasur vaccine virus strain showed CPE, 36-48 hr post infection. With both vaccine virus strains the CPE in vero cell...

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Antigenic and genomic comparison between non-cytopathic and cytopathic bovine viral diarrhoea viruses isolated from cattle that had spontaneous mucosal disease.

Antigenic and genomic relationships between five pairs of non-cytopathic and cytopathic bovine viral diarrhoea (BVD) viruses isolated from cattle with mucosal disease were examined. Antigenic similarity was evaluated by studying the binding characteristics of 10 monoclonal antibodies (MAbs) directed against the gp53 BVD virus glycoprotein. The MAb binding match between members of the same virus...

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Complete Genome Sequences of a Cytopathic/Noncytopathic Pair of Border Disease Viruses

The complete genome sequences of a cytopathic/noncytopathic pair of border disease viruses (BDV) that were isolated from a sheep with mucosal disease-like lesions were determined. The cytopathic virus possessed an insert of 288 nucleotides that was derived from the Jiv cellular transcript and had 37 nucleotide differences from the noncytopathic virus.

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 1990

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-71-5-1227